Follow-Up Study of Children with Precocious Puberty Treated with Cyproterone Acetate
نویسندگان
چکیده
منابع مشابه
Cyproterone acetate in treatment of precocious puberty.
Twenty-nine children (23 girls, 6 boys) with precocious puberty were treated with cyproterone acetate for various periods of time ranging from 6 months to 3 years 4 months. They received an oral dose ranging from 70-150 mg/m2 per day, or an intramuscular depot injection once a fortnight or once a month at a dose ranging from 107-230 mg/m2. Both forms of therapy were found to suppress the signs ...
متن کاملEffect of cyproterone acetate on adrenocortical function in children with precocious puberty.
Seven children with precocious puberty were treated with cyproterone acetate and their adrenal function studied. In each child the drug caused significant adrenal hypofunction which was secondary to adrenocorticotrophic hormone suppression. None of these children had clinical evidence of adrenal hypofunction and it is assumed that the drug has glucocorticoid-like properties. Children receiving ...
متن کاملWhether all patients with Central precocious puberty should be treated?
Extended Abstract Precocious puberty is the appearance of secondary sexual characteristics before 8 years old in girls and 9 years old in boys. Precocious puberty is divided into 3 groups of central, peripheral and normal variants. Central precocious puberty is accompanied by activation of hypothalamic-pituitary-gonadal axis which causes increase in secretion of GnRH, and in turn increase i...
متن کاملPrecocious puberty in children
OBJECTIVE To determine the etiology of precocious puberty in children and to compare the clinical and laboratory parameters of central and peripheral precocious puberty. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Endocrine Clinic at National Institute of Child Health, Karachi, from January 2009 to December 2011. METHODOLOGY Children presenting with precocious puberty ...
متن کاملLong-term Follow-up Study of Pulmonary Function Test in Children with History of Hydrocarbon Aspiration
Background Aspiration of hydrocarbons causes several acute and chronic pulmonary complications; it may even lead to death. The aim of this study was to investigate the types of long-term pulmonary complications in children with a history of hydrocarbon aspiration. Materials and Methods In this case-control study, 21 children ...
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ژورنال
عنوان ژورنال: Journal of Epidemiology
سال: 1997
ISSN: 0917-5040
DOI: 10.2188/jea.7.173